Microalgae has been recognized as a possible feedstock for the assembling of biofuels. On account of their natural nonpartisanship and adaptability underway, microalgae have arisen as a potential feasible biomass asset. Joining microalgae cultivation with wastewater treatment successfully lessens CO2 discharges and brings down the expense of delivering microalgae biofuel, making it more feasible. Preceding enormous scope creation, nonetheless, biomass and lipid efficiency should be expanded. Thus, the survey gives a basic appraisal of microalgae's usefulness for biofuel age, focusing on the influencing factors, for example, strains and culture conditions. In light of this review, we propose using a combination of nearby green growth species and a two-stage culture technique to accomplish an economical and practical microalgae biofuel creation involving wastewater as a medium. Despite its prospects as a biofuel feedstock, green growth's commitment to biofuel creation is restricted because of its significant expense and huge asset utilization.